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<i>Lophophora williamsii<_i> (Lem. ex Salm-Dyck) J. M. Coult.

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By Targets:	5-HT Receptor (1) Calcium Channel (1) Endogenous Metabolite (1) Fungal (1) Histone Methyltransferase (2) Potassium Channel (3)
By Research Areas:	Cancer (4) Infection (1) Inflammation/Immunology (1) Neurological Disease (6)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-114340

LEM-14	Histone Methyltransferase	Cancer
LEM-14 is a potent NSD2 inhibitor with an IC₅₀ of 132 µM. LEM-14 has the potential for the research of multiple myeloma .

HY-125244

LEM-14-1189	Histone Methyltransferase	Cancer
LEM-14-1189, a LEM-14 (HY-114340) derivative, is a NSDs inhibitor with IC₅₀s of 418 μM (NSD1), 111 μM (NSD2), and 60 μM (NSD3), respectively. The NSDs, histone lysine methyltransferases (HMTases), are oncoproteins, drivers of a number of tumors. LEM-14-1189 can be used for multiple myeloma (MM) research .

HY-12498

GV-58 1 Publications Verification	Calcium Channel	Neurological Disease
GV-58 is a novel N- and P/Q-type calcium (Ca ²⁺) channel agonist with EC₅₀s of 7.21 and 8.81 μM, respectively. GV-58 slows the deactivation of channels, resulting in a large increase in presynaptic Ca ²⁺ entry during activity. GV-58 can be used in lambert-eaton myasthenic syndrome (LEMS) research .

HY-14946

Amifampridine 3,4-Diaminopyridine	Potassium Channel	Neurological Disease
Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (K_v) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

HY-N4276

Nortracheloside	Others	Others
Nortracheloside is a lignan isolated from Trachelospermum jasminoides (Lindl.) Lem .

HY-N11708

(-)-Lariciresinol	Others	Cancer
(-)-Lariciresinol is a lignans that can be isolated from Sambucus williamsii. (-)-Lariciresinol stimulates UMR106 cell proliferation .

HY-14946A

Amifampridine phosphate 3,4-Diaminopyridine phosphate	Potassium Channel	Neurological Disease
Amifampridine (3,4-Diaminopyridine) phosphate is an orally active, potent and cell permeable voltage-gated potassium (K_v) channel blocker (PCB). Amifampridine phosphate is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine phosphate increases transmitter release from neuromuscular junctions (NMJs). Amifampridine phosphate can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

HY-14946R

Amifampridine (Standard)	Potassium Channel	Neurological Disease
Amifampridine (Standard) is the analytical standard of Amifampridine. This product is intended for research and analytical applications. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

HY-N0954

(+)-Pinoresinol diacetate	Fungal	Infection Inflammation/Immunology
(+)-Pinoresinol diacetate is an antifungal agent that can be isolated from Sambucus williamsii .

HY-N7588

Acetylvirolin	Others	Others
Acetylvirolin is a Lignans product that can be isolated from the herbs of Sambucus williamsii .

HY-N10098

Citrusin B	Others	Others
Citrusin B is a Lignans product that can be isolated from the stems of Sambucus williamsii .

HY-N11916

Kadsuphilin A	Others	Cancer
Kadsuphilin A can be extracted from Kadsura coccinea (Lem.) and has weak antiproliferative activity .

HY-129139

Cyanidin-3-O-arabinoside	Others	Others
Cyanidin-3-O-arabinoside is a pigment isolated from flowers of Rhododendron cv. Lems Stormcloud .

HY-N9153

erythro-Guaiacylglycerol-β-O-4’-sinapyl ether	Others	Others
erythro-Guaiacylglycerol-β-O-4’-sinapyl ether is a Lignans product that can be isolated from the stems of Sambucus williamsii. .

HY-115051

2-Hydroxymethyltetrahydropyran	Others	Others
2-Hydroxymethyltetrahydropyran is a volatile compound in Sambucus williamsii (SW) seed oil. SW seed oil has potential antioxidant activity .

HY-N8323

erythro-Guaiacylglycerol β-Sinapyl Ether 7-O-Glucoside	Others	Others
erythro-Guaiacylglycerol β-Sinapyl Ether 7-O-Glucoside is a Lignans product that can be isolated from the stems of Sambucus williamsii .

HY-W424017A

Lophophine hydrochloride	Endogenous Metabolite	Neurological Disease
Lophophine hydrochloride is the drug intermediate of anhalonine and Lophophorine (HY-119478), and can be found in Lophophora diffusa. Anhalonine causes slight sleepiness in frog. Lophophorine causes long-lasting convulsions, reflex excitability, muscle stiffness, and paralysis in rabbit and frog model .

HY-N1712

29-Hydroxyfriedelan-3-one 3-Oxo-29-hydroxyfriedelane	Others	Others
29-Hydroxyfriedelan-3-one (3-Oxo-29-hydroxyfriedelane) is a Lignans product that can be isolated from the stems of Sambucus williamsii .

HY-170908

Pellotine	5-HT Receptor	Neurological Disease
Pellotine is an alkaloid that can be isolated from Lophophora. Pellotine is the inverse agonist for 5-HT7 receptor with an EC₅₀ of 291 nM. Pellotine exhibits good affinity to 5-HT1DR and 5-HT6R with K_i of 117 nM and 170 nM. Pellotine reduces intracellular cAMP levels, thereby reducing neuronal excitability and neurotransmitter release .

HY-W002097R

1-(5-Methylthiophen-2-yl)ethan-1-one (Standard)	Others	Others
Amifampridine (Standard) is the analytical standard of Amifampridine. This product is intended for research and analytical applications. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

Nortracheloside	Apocynaceae Monophenols Classification of Application Fields Source classification Lignans Other Diseases Phenols Phenylpropanoids Plants Disease Research Fields Trachelospermum jasminoides (Lindl.) Lem.	Others
Nortracheloside is a lignan isolated from Trachelospermum jasminoides (Lindl.) Lem .

Cyanidin-3-O-arabinoside	Pigments Food Research	Others
Cyanidin-3-O-arabinoside is a pigment isolated from flowers of Rhododendron cv. Lems Stormcloud .

2-Hydroxymethyltetrahydropyran	Structural Classification Natural Products Caprifoliaceae Classification of Application Fields Source classification Other Diseases Sambucus williamsii Hance Plants Disease Research Fields	Others
2-Hydroxymethyltetrahydropyran is a volatile compound in Sambucus williamsii (SW) seed oil. SW seed oil has potential antioxidant activity .

(-)-Lariciresinol	Structural Classification Caprifoliaceae Source classification Lignans Phenols Polyphenols Sambucus williamsii Hance Phenylpropanoids Plants	Others
(-)-Lariciresinol is a lignans that can be isolated from Sambucus williamsii. (-)-Lariciresinol stimulates UMR106 cell proliferation .

(+)-Pinoresinol diacetate	Structural Classification other families Ketones, Aldehydes, Acids Source classification Adiantum capillus-veneris L. Plants	Fungal
(+)-Pinoresinol diacetate is an antifungal agent that can be isolated from Sambucus williamsii .

Acetylvirolin	Structural Classification Caprifoliaceae Source classification Lignans Sambucus williamsii Hance Phenylpropanoids Plants	Others
Acetylvirolin is a Lignans product that can be isolated from the herbs of Sambucus williamsii .

Citrusin B	Structural Classification Viburnaceae Source classification Lignans Phenylpropanoids Plants	Others
Citrusin B is a Lignans product that can be isolated from the stems of Sambucus williamsii .

Kadsuphilin A	Structural Classification Natural Products Source classification Kadsura philippinensis Elmer Plants Schisandraceae	Others
Kadsuphilin A can be extracted from Kadsura coccinea (Lem.) and has weak antiproliferative activity .

erythro-Guaiacylglycerol-β-O-4’-sinapyl ether	Structural Classification Caprifoliaceae Source classification Lignans Sambucus williamsii Hance Phenylpropanoids Plants	Others
erythro-Guaiacylglycerol-β-O-4’-sinapyl ether is a Lignans product that can be isolated from the stems of Sambucus williamsii. .

erythro-Guaiacylglycerol β-Sinapyl Ether 7-O-Glucoside	Structural Classification Viburnaceae Source classification Lignans Phenylpropanoids Plants	Others
erythro-Guaiacylglycerol β-Sinapyl Ether 7-O-Glucoside is a Lignans product that can be isolated from the stems of Sambucus williamsii .

29-Hydroxyfriedelan-3-one 3-Oxo-29-hydroxyfriedelane	Triterpenes Structural Classification Terpenoids Source classification Celastraceae Plants Euonymus alatus (Thunb.) Sieb.	Others
29-Hydroxyfriedelan-3-one (3-Oxo-29-hydroxyfriedelane) is a Lignans product that can be isolated from the stems of Sambucus williamsii .

1-(5-Methylthiophen-2-yl)ethan-1-one (Standard)	Structural Classification Natural Products Source classification Rubiaceae Plants Coffea arabica L.	Others
Amifampridine (Standard) is the analytical standard of Amifampridine. This product is intended for research and analytical applications. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .

Cat. No.	Compare	Product Name	Species	Source

HY-P7006AF

	Animal-Free BMP-2 Protein, Human/Mouse/Rat (His) Endogenous Mediator (Lem); Mononuclear Cell Factor (MCF)	Human	E. coli
	BMP-2 protein is an important member of the TGF-β superfamily and is critical in cardiogenesis, neurogenesis, and osteogenesis, inducing cartilage and bone formation. It initiates canonical BMP signaling by binding to BMPR1A and BMPR2, triggering BMPR2 phosphorylation and SMAD1/5/8 activation for gene transcription regulation. Animal-Free BMP-2 Protein, Human/Mouse/Rat (His) is the recombinant human-derived animal-Free BMP-2 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

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HY-P80783

	PGC1 alpha Antibody PPARGC1A; Lem6; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6	WB	Human, Mouse, Rat
	PGC1 alpha Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 91 kDa, targeting to PGC1 alpha. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P83728

	PGC1 alpha+beta Antibody (YA3458) Lem6 antibody; Ligand effect modulator 6 antibody; PERC antibody; Peroxisome proliferative activated receptor, gamma, coactivator 1 antibody; PGC 1 alpha antibody; PGC-1-beta antibody; PGC-1-related estrogen receptor alpha coactivator antibody; PGC1 antibody; PGC1A antibody; PGC1v antibody; PPAR gamma coactivator 1 alpha antibody; PPAR gamma coactivator-1 beta antibody; PPARGC 1 alpha antibody; PPARGC-1-beta antibody; PPARGC1 antibody; PPARGC1A antibody; Ppargc1b antibody; PRGC1_HUMAN antibody; PRGC2_HUMAN antibody;	WB	Human, Mouse, Rat
	PGC1 alpha+beta Antibody (YA3458) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3458), targeting PGC1 alpha+beta , with a predicted molecular weight of 91/113 kDa (observed band size:110 kDa). PGC1 alpha+beta Antibody (YA3458) can be used for WB experiment in human, mouse, rat background.

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<i>Lophophora williamsii<_i> (Lem. ex Salm-Dyck) J. M. Coult.

Inhibitors & Agonists

NaturalProducts

Recombinant Proteins

Antibodies

Natural
Products